ASCE+ and PRP biostimulation

Biostimulation targets improvement in tissue quality and function. Its purpose is not to change facial features or artificially increase volume, but to support natural skin renewal processes.

At Slim & Smile Aesthetic Clinic, we use two modern biostimulation methods:

• ASCE+ exosome therapy,
• platelet-rich plasma PRP.

Both therapies may be used independently or as part of an individually planned regenerative programme, including after laser treatments, microneedling and microneedle radiofrequency.

ASCE+ is a professional regenerative formula using exosomes, microscopic extracellular vesicles involved in signalling between cells.

Exosomes are not stem cells. They carry biological information and signalling components that support cellular communication and the skin’s natural renewal processes.

ASCE+ therapy may support:

• skin regeneration,
• improved skin density and elasticity,
• smoothing fine lines,
• a more even skin tone,
• reduced pore visibility,
• improved appearance of skin with signs of photoageing,
• reduced redness and post-treatment discomfort,
• restoration of the skin’s protective barrier,
• improved scalp condition.

The therapy may be suitable for people whose skin is:

• dry and dehydrated,
• thin and lacking elasticity,
• tired or lacking radiance,
• exposed to chronic stress and environmental factors,
• uneven in texture or tone,
• weakened by sun exposure,
• in need of regeneration after intensive procedures.

ASCE+ may also be used for a scalp requiring strengthening and improved overall condition.

The preparation may complement procedures that create controlled microchannels or temporarily increase epidermal permeability. This allows active ingredients to be applied evenly to properly prepared skin.

Following assessment and in accordance with a developed protocol, ASCE+ may be combined with:

• the Lavieen thulium laser,
• Secret RF microneedle radiofrequency,
• microneedling,
• other treatments aimed at skin remodelling.

ASCE+ is used in accordance with its intended purpose and treatment protocol. We do not present it as a preparation intended for conventional needle injection.

As regeneration progresses, skin may become more even, elastic, smooth and radiant. Treatment may also help soothe and restore skin following procedures that cause controlled tissue injury.

Results depend on the skin’s initial condition, the procedure performed and the individual treatment plan.

PRP, or platelet-rich plasma, is obtained from a small amount of blood taken from the patient. After appropriate centrifugation, a plasma fraction with a higher platelet concentration is separated.

Platelets release growth factors and other substances involved in repair processes. Their action may support fibroblast activity, extracellular matrix remodelling and production of components responsible for skin firmness and elasticity.

Because autologous material obtained directly from the patient is used, PRP is a natural biostimulation method.

Platelet-rich plasma may be used to:

• improve skin quality and density,
• support natural skin regeneration,
• smooth fine lines,
• improve elasticity and tightness,
• refresh the skin of the face, neck and décolletage,
• regenerate delicate skin around the eyes,
• improve the appearance of the hands,
• support scar therapy,
• improve scalp condition and support treatment of excessive hair loss.

PRP may be chosen by people who prefer treatments using their own biological material, without conventional fillers.

The first stage is a consultation and eligibility assessment. A small amount of the patient’s blood is then taken and centrifuged in a dedicated system.

The resulting platelet-rich plasma is administered to selected skin areas using a method suited to the indication and planned result. Treatment may be performed manually or with appropriately selected delivery technology.

Redness, mild swelling, tenderness, small bruises or briefly visible preparation deposits may occur immediately afterwards.

PRP does not act like a conventional filler, so results are not immediate. Improvement occurs gradually as regenerative processes develop.

Over time, skin may become tighter, more elastic, smoother and better nourished. A series of treatments followed by maintenance sessions is most often recommended. Their number and frequency are determined individually.

The choice depends on skin condition, the desired result and the planned procedures.

• intensive support for regeneration after treatment is desired,
• skin needs improved tone and texture,
• biostimulation is to be combined with a laser or microneedle radiofrequency,
• support for the protective barrier and skin soothing are desired.

• the patient prefers autologous treatment,
• gradual improvement in skin quality is desired,
• treatment covers the face, neck, décolletage, eye area or hands,
• the aim is to support scalp condition,
• the natural potential of growth factors from the patient’s blood is to be used.

In selected cases, combined or alternating treatment may be planned.

Every therapy is preceded by a consultation. The specialist assesses skin condition, previous treatments, medicines and contraindications.

Contraindications may include pregnancy and breastfeeding, active infections, skin inflammation, certain autoimmune diseases and cancers, clotting disorders and use of particular medicines.

For PRP, blood count results, platelet number and function, and the patient’s overall health also matter.

At Slim & Smile Aesthetic Clinic, we tailor the biostimulation method to the skin’s actual needs. ASCE+ and PRP can form part of a comprehensive regenerative programme combining medicine, modern technology and an informed approach to natural rejuvenation.

Our aim is to improve skin quality without changing its natural character.